Progressive medullary failure associated with neurofibrillary degeneration.
نویسندگان
چکیده
منابع مشابه
Progressive medullary failure associated with neurofibrillary degeneration.
A clinicopathological report is presented of a British male, aged 59 years, who died after an illness of 10 years, manifested by progressive respiratory failure, ptosis, and dysphagia. At no time was there evidence of ophthalmoplegia, Parkinsonism or dementia. At necropsy the main finding was of neurofibrillary tangles in the neurons of the pontine and medullary reticular formation, with partic...
متن کاملNeurofibrillary degeneration in progressive supranuclear palsy and corticobasal degeneration: tau pathologies with exclusively "exon 10" isoforms.
Pathological tau proteins that constitute the basic matrix of neuronal inclusions observed in numerous neurodegenerative disorders are disease specific. This is mainly the consequence of the aggregation of specific sets of tau isoforms according to the diseases, i.e., six isoforms in Alzheimer's disease (AD) and exclusively the three tau isoforms lacking the corresponding sequence of exon 10 (E...
متن کاملRapidly progressive renal failure associated with successful pharmacotherapy for obesity.
Reply Sir, We thank Drs Calo and Davis for highlighting their interesting studies. We were, in fact, aware of these studies and have used them as background in grant applications in the broader context. Our paper was not intended to be a review of the literature, since this area, we believe, is still evolving. It is always a subjective decision which references to include or not in any given pu...
متن کاملRapidly progressive renal failure associated with successful pharmacotherapy for obesity
A 55-year-old woman presented with recurrent episodes of hypoglycaemia over 4 weeks. She had had type 1 diabetes mellitus (DM) for 35 years, managed by an insulin basal bolus regime. Her comorbidities included retinopathy, chronic renal failure, (presumed to be on the basis of diabetic nephropathy), hypertension, obesity, gout and an ischaemic stroke 15 years earlier. Over 5 years of follow-up,...
متن کاملProgressive multifocal leukoencephalopathy with wallerian degeneration.
A 39-year-old male presented with slurred speech, left hand weakness, gait unsteadiness and headaches over a period of 4 weeks. A brain MRI revealed a right motor strip lesion with Wallerian degeneration along the pyramidal tract plus brain stem and cerebellar FLAIR changes without enhancement ( fig. 1 ). Laboratory findings included a CD4 count of 56, HIV viral load of 2,597 and a positive CSF...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1989
ISSN: 0022-3050
DOI: 10.1136/jnnp.52.5.643